Understanding CJC-1295 with DAC
The key difference in this peptide is the addition of the Drug Affinity Complex (DAC). This is a chemical modification that allows the CJC-1295 peptide to bind to albumin, a protein circulating in your blood. This binding protects the peptide from rapid degradation, transforming it from a short-acting compound into a long-acting one.
How Does the DAC Feature Work?
- Extended Half-Life: The DAC feature extends the half-life from minutes to approximately 8 days.
- Sustained Release: This creates a continuous stimulation of the pituitary gland, leading to a steady elevation of GH and IGF-1 levels around the clock. This is often referred to as a “GH bleed.”
- Maximum Convenience: Because of its long duration, it requires much less frequent administration, typically only once or twice per week.
Why Choose CJC-1295 with DAC?
The primary reason to choose this version is for convenience and to maintain consistently elevated growth hormone levels without the need for multiple daily injections. It is a powerful tool for long-term anti-aging and wellness protocols.
Key Benefits of a Sustained GH Elevation:
- Consistent support for fat metabolism and energy.
- Prolonged stimulation of IGF-1, which is crucial for cellular repair and growth.
- Systemic benefits for skin, bone, and connective tissues.
- Simplified dosing schedule enhances protocol adherence.
Note: Because CJC-1295 with DAC overrides the natural GH pulse, it is generally not stacked with a GHRP like Ipamorelin, as doing so would be redundant and less effective.
| Feature | CJC-1295 without DAC (Mod GRF 1-29) | CJC-1295 with DAC |
|---|---|---|
| Also Known As | Mod GRF 1-29 | Long-Acting CJC-1295 |
| Half-Life | ~30 minutes | ~8 days |
| Mechanism | Creates a short, strong, natural “pulse” of GH. | Creates a sustained “bleed” or elevation of GH. |
| Dosing Frequency | 1-3 times per day | 1-2 times per week |
| Stacking | Excellent. Almost always stacked with Ipamorelin. | Not Recommended. Used as a standalone GHRH. |
| Primary Goal | Mimic a natural, physiologic GH pulse for maximum synergy. | Provide convenience and sustained GH/IGF-1 levels. |
| Best For | Athletes, body composition, mimicking natural body rhythms. | Long-term wellness, anti-aging, convenience. |
















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