CJC-1295 without DAC (Modified GRF 1-29)
CJC-1295 without DAC, accurately known as Modified GRF (1-29), is a fast-acting Growth Hormone Releasing Hormone (GHRH) analog for scientific research. Engineered for stability but with a short half-life, it is the premier choice for laboratory studies that require mimicking the body’s natural, pulsatile release of growth hormone. Each vial contains lyophilized powder of the highest purity (≥99%), verified by third-party HPLC testing.
Key Characteristics & Mechanism
- Also Known As: Mod GRF 1-29, CJC-1295 no DAC
- Classification: Tetrasubstituted Peptide, GHRH Analog
- Half-Life: Approximately 30 minutes.
- Mechanism: Binds to GHRH receptors on the pituitary gland, stimulating a strong, short-lived pulse of growth hormone (GH) release.
- Primary Research Function: To study the effects of discrete, naturalistic GH pulses.
Research Application Highlights
Mod GRF 1-29 is a critical tool for researchers investigating:
- Pulsatile Hormone Secretion: Ideal for protocols requiring multiple, timed administrations to simulate natural endocrine rhythms.
- Synergistic Effects: Commonly researched alongside GHRPs (like Ipamorelin or GHRP-2) to study maximal, amplified GH release.
- Short-Term Metabolic Effects: Investigating the immediate impact of a GH pulse on processes like lipolysis and protein synthesis.
- Endocrine Feedback Loops: Analyzing how the hypothalamus-pituitary axis responds to and recovers from a GHRH stimulus.
Mod GRF 1-29 vs. CJC-1295 with DAC: The Critical Distinction
Choosing the correct compound is essential for valid experimental results.
| Feature | CJC-1295 without DAC (Mod GRF 1-29) | CJC-1295 with DAC |
|---|---|---|
| Action | Fast-Acting | Long-Acting |
| Half-Life | ~30 minutes | ~8 days |
| GH Release | Strong, Pulsatile Burst | Sustained “Bleed” / Elevated Baseline |
| Research Use | Mimics natural GH pulses | Creates a stable, long-term GH elevation |
| Administration | More Frequent (e.g., daily) | Infrequent (e.g., weekly) |
Product Specifications
- Chemical Name: Modified GRF (1-29)
- Purity: ≥99% (Confirmed by HPLC)
- Appearance: White Lyophilized Powder
- Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂
- Storage: Store lyophilized powder at -20°C. Once reconstituted, refrigerate at 2-8°C.
- Intended Use: For laboratory and research applications only.
IMPORTANT: For Laboratory Research Only
This product is a chemical compound sold exclusively for in-vitro testing and laboratory experimentation. It is NOT for human or veterinary consumption. It is not a drug, food, or cosmetic and must not be used for any purpose other than its intended research application. By purchasing, you confirm that you are a qualified professional working within a properly equipped research facility.
















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